The Oklahoma City Thunder look to remain perfect on the year when they battle the San Antonio Spurs in an NBA Western Conference matchup on Wednesday night. Oklahoma City cruised to a 128-104 win over the Atlanta Hawks on Sunday, while San Antonio dropped a 106-101 decision to the Houston Rockets on Monday. The Spurs (1-2), who were 22-60 a year ago, are 10-32 on the road since the start of last season. The Thunder (3-0), the top seed in the West at 57-25 in 2023-24, are 34-8 at home since the beginning of last season.

Tip-off from Paycom Center in Oklahoma City is set for 9:30 p.m. ET. The Spurs lead the all-time regular-season series 101-87, but the Thunder have won six of the last seven meetings. The Thunder are 12.5-point favorites in the latest Spurs vs. Thunder odds from SportsLine consensus, while the over/under for total points scored is 221.5. Before making any Thunder vs. Spurs picks, you’ll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 2 of the 2024-25 NBA season on a sizzling 98-63 roll on all top-rated NBA picks dating back to last season, returning more than $2,900. Anyone following at sportsbooks and on betting apps has seen huge returns. 

The model has set its sights on Spurs vs. Thunder and just locked in its picks and NBA predictions. You can head to SportsLine now to see its picks. Here are several NBA betting lines for Thunder vs. Spurs:

• Spurs vs. Thunder spread: Oklahoma City -12.5
• Spurs vs. Thunder over/under: 221.5 points
• Spurs vs. Thunder money line: Oklahoma City -806, San Antonio +555
• SA: The Spurs have hit the money line in 12 of their last 26 games (+19.40 units)
• OKC: The Thunder have covered the spread in 29 of their last 44 games at home (+12.50 units)  
• Spurs vs. Thunder picks: See picks at SportsLine
• Spurs vs. Thunder streaming: FuboTV (Try for free)

Why the Thunder can cover

Veteran point guard Shai Gilgeous-Alexander is coming off a near triple-double with 35 points, 11 rebounds and nine assists in the win over the Hawks on Sunday. He had 28 points, eight assists and seven rebounds in a 102-87 win at Denver on opening night. For the season, he is averaging 28.7 points, 8.7 rebounds, 6.3 assists, three steals and two blocks in 34 minutes of action. He is connecting on 44.9% of his field goals and 89.5% of his free throws.

Power forward Chet Holmgren is one of four players averaging double-digit scoring. Through the first three games of the season, Holmgren is averaging 23.7 points, 13 rebounds, four blocks, three assists and 1.3 steals in 32.7 minutes. He has two double-doubles on the year and nearly had a third in the win over the Hawks. In the season-opening win at Denver on Thursday, he scored 25 points, grabbed 14 rebounds, dished out five assists and blocked four shots. See which team to pick here.

Why the Spurs can cover

Second-year veteran center Victor Wembanyama is off to a fast start to the season. He is averaging a double-double with 20 points and 12 rebounds, and is adding 2.7 blocks and 2.3 assists in 31.3 minutes of action. In Monday’s loss to Houston, he grabbed a season-high 20 rebounds and scored 14 points with five assists and four blocks. He had 29 points, seven boards and three blocks in Saturday’s win over the Rockets.

Forward Jeremy Sochan has one double-double and three double-digit scoring games this season. In a 109-106 win over Houston on Saturday, he scored 17 points, while grabbing 12 rebounds in 37 minutes. He had 22 points, nine rebounds and four assists in Monday’s loss to the Rockets. For the season, he is averaging 19 points, nine rebounds and three assists in 32.7 minutes. See which team to pick here.

How to make Spurs vs. Thunder picks

The model has simulated Spurs vs. Thunder 10,000 times and the results are in. The model is leaning Under on the total, projecting 221 combined points. It also says one side of the spread hits in nearly 70% of simulations. You can only see the pick at SportsLine.

So who wins Spurs vs. Thunder, and which side of the spread hits nearly 70% of the time? Visit SportsLine now to see which side of the Spurs vs. Thunder spread you need to jump on, all from the model that is on a 98-63 roll on top-rated NBA picks, and find out.