Fresh layoffs have jolted the Bay Area, staffing reductions that are poised to eliminate about 600 jobs in the retail, grocery, tech, biotech, and food manufacturing industries, official state labor notices show.

Safeway, Draeger’s Supermarkets, AppLovin, IGM Biosciences, Aurora Solar and Columbus Manufacturing have revealed plans for job cuts that will affect workers in the South Bay and the East Bay, on the Peninsula, and in San Francisco, according to WARN letters sent to the state Employment Development Department.

All told, the staffing cuts will eliminate 599 Bay Area jobs, the EDD documents show.

Here are the details for the recent staffing reductions in the Bay Area:

— Safeway, 156 job cuts at two office locations in Pleasanton. These are all corporate positions and none are at Safeway supermarkets. The layoffs are due to occur Feb. 22.

— Columbus Manufacturing, a producer of meats such as salami, 125 layoffs in Hayward, slated to occur on March 15.

— IGM Biosciences, 100 staffing reductions in Mountain View, scheduled for March 10.

— AppLovin, 89 job cuts in Palo Alto. The terminations occurred on Jan. 15.

— Draeger’s Supermarkets, 71 layoffs in San Mateo. The cutbacks are associated with the grocery store’s closure and are slated to occur March 10.

— Aurora Solar, 58 staff cuts in San Francisco. The provider of software to design solar systems said the staff reductions occurred on Jan. 10.

The job cuts were all described as permanent, according to the WARN notices.

However, in at least one instance, the Draeger’s Market closure, it was possible that some workers might be able to find jobs at other Draeger’s locations.

“Certain employees covered by a collective bargaining agreement with United Food and Commercial Workers Local 5 may have seniority bumping rights which enable them to transfer to another store,” Draeger’s wrote in the WARN letter.