A Big Ten battle will take place on Sunday when the Purdue Boilermakers host the Nebraska Cornhuskers. The Boilermakers are currently ranked No. 20 in the AP Top 25 after a 12-4 start and a 4-1 record in conference play. Meanwhile, the Cornhuskers are 12-3 on the season and 2-2 in the league. Purdue has won four of the last five head-to-head matchups but Nebraska has managed to cover the spread in two of the past three meetings.

Tipoff is set for noon ET at Mackey Arena in West Lafayette, Ind. The Boilermakers are favored by 8.5 points in the latest Purdue vs. Nebraska odds, while the over/under is 140.5 points per SportsLine consensus. Before entering any Nebraska vs. Purdue picks, you’ll want to see the college basketball predictions from the proven computer model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 10 of the 2024-25 season on an 189-130 betting roll (+2985) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Purdue vs. Nebraska. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

• Purdue vs. Nebraska spread: Purdue -8.5
• Purdue vs. Nebraska over/under: 140.5 points
• Purdue vs. Nebraska money line: Purdue -394, Nebraska +307
• Purdue vs. Nebraska picks: See picks here
• Purdue vs. Nebraska streaming: FuboTV (Try for free)

Why Purdue can cover

It’s already been a rollercoaster season for the Boilermakers, who won their first four games, had a 4-4 stretch, and now have won four games in a row once again (all by double-digits). Most recently, Purdue managed a 68-50 win over Rutgers on Thursday as 4-point favorites on the road.

Braden Smith controlled the action on both ends of the floor, finishing with 16 points, 14 assists, three rebounds, three steals and a blocked shot. The third-year guard led the Big Ten in assists (7.5 assists per game) last season and he’s been even better in 2024-25, leading the conference with 8.9 assists per game. Purdue has covered the spread in three consecutive games. See which team to pick here. 

Why Nebraska can cover

Meanwhile, Nebraska had a six-game winning streak snapped on the road against Iowa on Tuesday. Brice Williams had a monster effort with 28 points but that wasn’t enough to save the Cornhuskers from a 97-87 defeat at the hands of their border rivals. They allowed the Hawkeyes to go 17-for-35 from the 3-point line.

However, that was an uncharacteristic outing from Fred Hoiberg’s squad, which ranks 21st in the nation in field-goal percentage defense (38.8%) and has only allowed opponents to shoot 30.8% from beyond the arc this year. Nebraska has covered the spread in nine of its last 12 games entering Sunday. See which team to pick here. 

How to make Purdue vs. Nebraska picks

The model has simulated Nebraska vs. Purdue 10,000 times and the results are in. The model is leaning over on the total, and it’s also generated a point-spread pick that is hitting in well over 50% of simulations. You can only see the pick at SportsLine.

So who wins Purdue vs. Nebraska, and which side of the spread hits well over 50% of the time? Visit SportsLine now to see which side of the Nebraska vs. Purdue spread you need to jump on, all from the model on an 189-130 roll on top-rated college basketball picks, and find out.