The Los Angeles Lakers will be looking to continue their dominance against the Detroit Pistons in a cross-conference matchup tonight in the Motor City. 

My Lakers vs. Pistons predictions have LeBron James & Co. bringing their best for the second-last game of this road trip. Keep reading for my NBA picks for Monday, November 4.

Lakers vs Pistons prediction

My best bet
Lakers -6.5 (-110 at bet365)

My analysis
The Los Angeles Lakers are off to a respectable 4-2 start to begin the 2024-25 campaign. Offensively, L.A. is producing the goods, averaging the sixth-most points per game in the Association. While JJ Redick is still trying to instill his defensive mindset in this team, they’re showing a lot of promise so far. 

The Detroit Pistons also happen to be a team the Lakers have owned for over three years now. Dating back to February of 2021, the Purple and Gold have won seven in a row against Detroit. Last season, L.A. won both meetings against the Pistons, outscoring them by 40 points across the two victories. 

The Lakers have covered the spread in four straight matchups as well. The two wins in 2022-23 came by seven points apiece. L.A. is beating teams by an average of six points this season, but given their past success against Detroit, I believe they can cover for a fifth consecutive clash with one of the worst teams in the league. 

If you need more evidence, the Pistons are losing by an average of 10.4 points and just fell to the Knicks by 20 points on Friday on home court before beating the Nets on Sunday. Detroit hasn’t won at Little Caesars Arena yet. 

Lakers vs Pistons same-game parlay (SGP)

The Lakers are putting up 118.3 points per game, while Detroit is scoring just 104.8 per night. However, this matchup has been very high-scoring in recent seasons. The last four comfortably hit the Over. In fact, the Under has cashed only once in the previous seven meetings dating back to 2021.

The common trend between L.A. and Detroit is either the Lakers score a lot of points and the Pistons don’t, or they both erupt offensively, and there’s minimal defense played. As previously mentioned, neither club is playing well defensively, while the Lake Show is putting up points. 

Anthony Davis is expected to play despite a hip issue and has been balling out, scoring 30+ points in four of the six games in ‘24-25. His presence will be important in the Over being hit here, whether it’s a close contest or a lopsided one.

Learn how to bet a same-game parlay with these helpful tips and strategies.

Lakers vs Pistons odds

Lakers vs Pistons live odds

Get the latest Lakers vs. Pistons NBA odds.

Lakers vs Pistons opening odds

• Spread: Los Angeles -6.5 | Detroit +6.5
• Moneyline: Los Angeles -270 | Detroit +220
• Over/Under: Over 227.5 | Under 227.5

Lakers vs Pistons spread and Over/Under analysis

• The Lakers are 4-2 ATS this season.
• The Over 227 has hit in four straight meetings.
• L.A. was 32-14 as a moneyline favorite last season. 
• Detroit is just 3-6-1 ATS in its last 10 games.

Lakers vs Pistons trend

The Lakers have only stayed Under the total in 31 of their last 79 games (-20.65 units / -24% ROI). Find more NBA betting trends for Lakers vs. Pistons.

Lakers vs Pistons game info

Lakers vs Pistons latest injuries

Pages related to this topic