The Detroit Pistons will host the Los Angeles Lakers for a cross-conference clash on Monday. The Lakers are off to a 4-2 start on the season and are currently fifth in the West, while the Pistons are 2-5 and are 13th in the East. Los Angeles has won and covered the spread in its last four head-to-head meetings with Detroit, but the Pistons have covered in four of their last five games overall.

Tipoff from the Little Caesars Arena in Detroit is set for 7:30 p.m. ET. The SportsLine consensus lists Los Angeles as the 7.5-point favorite in the latest Lakers vs. Pistons odds, while the over/under for total points scored is 227.5. Before making any Pistons vs. Lakers picks, you’ll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 3 of the 2024-25 NBA season on a sizzling 101-64 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following at sportsbooks and on betting apps has seen huge returns.

The model has set its sights on Pistons vs. Lakers and just locked in its picks and NBA predictions. You can head to SportsLine now to see its picks. Here are several NBA betting lines for Lakers vs. Pistons:

• Pistons vs. Lakers spread: Pistons +7.5
• Pistons vs. Lakers over/under: 227.5 points
• Pistons vs. Lakers money line: Pistons +238, Lakers -296
• DET: The under has hit in seven of Detroit’s last nine games    
• LAL: The over has hit in four of Los Angeles’ last five games 
• Pistons vs. Lakers picks: See picks at SportsLine
• Pistons vs. Lakers streaming: FuboTV (Try for free)

Why the Pistons can cover

Detroit is coming off a 106-92 win over Brooklyn on Sunday and had six different players reach double-figures in scoring. Cade Cunningham led the way with 19 points, and Jalen Duren posted a double-double with 13 points, 17 rebounds, four assists, three blocks and a steal.

The Pistons overcame 21 turnovers by limiting the Nets to just 9-for-31 shooting from the 3-point line. It was their second win in their last three outings, and they’ve now covered the spread in four of their last six games when playing as an underdog. Detroit could face a Lakers team without starting point guard D’Angelo Russell (foot) who is listed as questionable. See which team to pick here.

Why the Lakers can cover

The Lakers captured a 131-125 victory over the Raptors on Friday and have had a couple of days off to recover. Anthony Davis had 38 points and 11 rebounds in the victory, and he’s listed as probable for Monday’s matchup with a hip injury.

LeBron James also had a double-double with 27 points and 10 assists in the win. Austin Reaves had 20 points and six assists while the Lakers lived at the charity stripe, knocking down 36 of 41 free throws, while limiting Toronto to just 13 free throw attempts. Los Angeles has now covered the spread in six of its last eight games. See which team to pick here.

How to make Pistons vs. Lakers picks

The model has simulated Lakers vs. Pistons 10,000 times and the results are in. The model is leaning over on the point total, and it also says one side of the spread hits over 60% of the time. You can only see the pick at SportsLine.

So who wins Pistons vs. Lakers, and which side of the spread hits over 60% of the time? Visit SportsLine now to see which side of the Lakers vs. Pistons spread you need to jump on, all from the model that is on a 101-64 roll on top-rated NBA picks since last season, and find out.