The Liberty Flames will look to get back on track when they battle the Jacksonville State Gamecocks in a key Conference USA matchup Wednesday night on CBS Sports Network. Jacksonville State is coming off a 42-20 win over Middle Tennessee State in Week 9, while Liberty dropped a 27-24 decision at Kennesaw State. It was Liberty’s first-ever loss as a member of C-USA. The Gamecocks (4-3, 3-0 C-USA), who are tied for first in the conference with Western Kentucky, have won four in a row. The Flames (5-1, 3-1 C-USA), who are tied for third in the league with Sam Houston, had an 11-game conference winning streak snapped last week.

Kickoff is set for 7 p.m. ET at Williams Stadium in Lynchburg, Va. Jacksonville State leads the all-time series 4-1, but Liberty earned a 31-13 win in last year’s meeting. The Flames are 2.5-point favorites in the latest Jacksonville State vs. Liberty odds, while the over/under for total points scored is 63. Before making any Liberty vs. Jacksonville State picks, check out the college football predictions from the SportsLine Projection Model.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a betting profit of well over $2,000 for $100 players on its top-rated college spread football picks, and it is a sizzling 16-7 on all top-rated picks over the past five weeks of this season. Anyone following at sportsbooks and on betting apps has seen strong returns.

The model has set its sights on Jacksonville State vs. Liberty. You can head to SportsLine to see its picks. Here are several college football betting lines and trends for Liberty vs. Jacksonville State:

• Jacksonville State vs. Liberty spread: Liberty -2.5
• Jacksonville State vs. Liberty over/under: 63 points
• Jacksonville State vs. Liberty money line: Liberty -129, Jacksonville State +107
• JSU: The Gamecocks have hit the game total over in 8 of their last 11 games (+4.70 units)  
• LIB: The Flames have hit the game total over in 7 of their last 12 games (+2.60 units)  
• Jacksonville State vs. Liberty picks: See picks at SportsLine
• Jacksonville State vs. Liberty streaming: FuboTV (Try for free)

Why you should back Liberty

Redshirt junior quarterback Kaidon Salter is a dual threat for the Flames. He has completed 97 of 159 passes (61%) for 1,280 yards and 10 touchdowns with two interceptions and a 146.9 rating. He has also carried 61 times for 278 yards (4.6 average) and two touchdowns. In last week’s loss to Kennesaw State, Salter completed 22 of 40 passes (55%) for three touchdowns and one interception.

Senior running back Quinton Cooley is Liberty’s top running back. He has carried 91 times for 582 yards (6.4 average) and six touchdowns. He has had four 100-plus rushing games, including in two of his past three games. In a 31-24 overtime win over Florida International on Oct. 8, he carried 29 times for 174 yards (6.0 average) and two touchdowns. See which team to pick here.

Why you should back Jacksonville State

Sixth-year senior quarterback Tyler Huff has led the Gamecocks offense this season. The dual-threat leads the team in passing and is second in rushing. He has completed 99 of 152 passes (65.1%) for 1,406 yards and eight touchdowns with four interceptions and a rating of 154.9. He has carried 94 times for 654 yards (7.0 average) and eight touchdowns. In last week’s win over Middle Tennessee State, he completed 10 of 18 passes for 137 yards and one touchdown, and rushed 18 times for 151 yards and two scores.

Senior running back Tre Stewart has been on a tear. He has rushed for 100 or more yards in each of the last three games, including 21 carries for 210 yards and one touchdown last week against MTSU. He also had two receptions for 24 yards. In a 63-24 win at Kennesaw State on Oct. 4, he carried 24 times for 134 yards and four touchdowns. For the season, Stewart has rushed 107 times for 682 yards (6.4 average) and 11 touchdowns. See which team to pick here.

How to make Jacksonville State vs. Liberty picks

SportsLine’s model is leaning Over on the total, projecting 65 combined points. It also says one side of the spread hits in well over 50% of simulations. You can only get the pick at SportsLine.

So who wins Jacksonville State vs. Liberty, and which side of the spread cashes in well over 50% of simulations? Visit SportsLine now to see which side of the spread to jump on, all from the advanced model that is up well over $2,000 on its FBS college football picks since its inception, and find out.