The No. 14 Houston Cougars (10-3) will try to extend their 30-game home winning streak when they host the TCU Horned Frogs (8-5) on Monday night. Houston has won six straight games since losing to San Diego State in overtime at the end of November, notching an 86-55 win over BYU on Saturday. TCU has won three of its last four games, including a 63-62 win against Kansas State over the weekend. These teams split the season series last year, with the home team winning on both occasions. 

Tipoff is set for 9 p.m. ET on Monday at the Fertitta Center. Houston is favored by 18.5 points in the latest Houston vs. TCU odds, while the over/under is 128.5 points, per SportsLine consensus. Before entering any TCU vs. Houston picks, you’ll want to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 10 of the 2024-25 season on a 189-130 betting roll (+2985) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen huge returns.

The model has set its sights on TCU-Houston. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the game:

• Houston vs. TCU spread: Houston -18.5
• Houston vs. TCU over/under: 128.5 points
• Houston vs. TCU money line: Houston: -4545, TCU: +1513
• Houston vs. TCU picks: See picks here
• Houston vs. TCU streaming: FuboTV (Try for free)

Why Houston can cover

Houston has been consistently blowing teams out during its current winning streak, wrapping up non-conference play with four wins by 20-plus points. The Cougars opened the Big 12 portion of their schedule with a 60-47 win at Oklahoma State, as senior forward J’Wan Roberts posted a double-double with 20 points and 11 rebounds. They followed that performance with an 86-55 win over BYU on Saturday, easily covering the spread as 10-point favorites. 

Junior guard Emanuel Sharp led the way with 18 points on 5 of 9 shooting, while sophomore guard Terrance Arceneaux had 15 points and six rebounds off the bench. BYU entered that game ranked 24th nationally in offensive efficiency, according to KenPom, but it was held to 37.5% shooting and its lowest point total of the season. The Cougars are averaging 75.3 points per game during their six-game winning streak. See which team to pick here. 

Why TCU can cover

TCU used a late 7-0 run to pick up a 63-62 win over Kansas State on Saturday, giving the Horned Frogs three wins in their last four games. Senior guard Brendan Wenzel returned from an injury absence, scoring three points and grabbing two rebounds off the bench. Senior guard Noah Reynolds scored a team-high 18 points on 7 of 13 shooting, while sophomore guard Vasean Allette had 14 points and three assists. 

Trazarien White finished with 14 points and three 3-pointers to mark his ninth double-digit scoring game this season. The Horned Frogs were 3-point home underdogs when they took down Houston last season in a 68-67 final. They have covered the spread in six of their last eight Monday games. See which team to pick here.

How to make Houston vs. TCU picks

The model has simulated TCU vs. Houston 10,000 times and the results are in. We can tell you that the model is leaning Over, and it’s also generated a point-spread pick that is hitting in over 50% of simulations. You can only see the pick at SportsLine.

So who wins Houston vs. TCU, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the TCU vs. Houston spread you need to jump on, all from the model on a 189-130 roll on top-rated college basketball picks, and find out.