The Lions will host the Bills in one of the most highly anticipated matchups of the season Sunday. 

Over the years, Bills quarterback Josh Allen has proven he shows out for big games, even if he has yet to win “The Big Game” so far. 

Allen has made a habit of taking matters into his own hands in games like this throughout his NFL career. 

In fact, he proved so last Sunday when Allen ran for 82 yards and three touchdowns in a thrilling 44-42 loss to the Rams. 

Bills vs. Lions odds

Bills vs. Lions prediction

4:25 p.m. ET, CBS

Three weeks earlier, Allen ran for 55 yards during the Bills’ win over the Chiefs to hand them their first loss.

In 10 career playoff games, Allen is averaging 56.3 rushing yards, including 146 total yards on the ground in two postseason games last year. 

Now, this isn’t a playoff game and the Bills don’t need to win Sunday to earn a No. 2 or No. 3 seed in the AFC. 

But Allen and Co. no doubt want to take down the team viewed as the Super Bowl favorite right now. 

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And, of course, there’s that elusive MVP award that Allen is chasing. 

The Lions haven’t been an easy task at all for opposing quarterbacks this season, but they are letting them get outside the pocket and up field a bit. 

Their 24.9 rushing yards allowed to quarterbacks in 2024 are the seventh-most in the NFL. 

Bet on the Bills quarterback to tuck and run more than usual Sunday. 

The play: Josh Allen Over 36.5 rushing yards (-115, DraftKings Sportsbook)

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Dylan Svoboda is a versatile writer and analyst across many sports. He’s particularly knowledgeable about the big three — MLB, the NFL and the NBA.