The UConn Huskies will take on the Colorado Buffaloes on Tuesday in the 2024 Maui Invitational following the first loss of the season for the two-time defending national champions. UConn lost to Memphis, 99-97, in overtime in the opening round of the Maui Invitational on Monday to fall to 4-1. Colorado lost to Michigan State, 72-56, on Monday in its first game of the Maui Invitational 2024 to drop to 4-1 overall this season. Monday was Connecticut’s first loss since Feb. 20, 2023 to break a 17-game winning streak, including postseason play.

Tipoff is set for 3:30 p.m. ET from Lahaina Civic Center in Lahaina, Hawaii. UConn is a 15.5-point favorite in the latest Colorado vs. UConn odds, while the over/under is 143.5 points per SportsLine consensus. Before entering any UConn vs. Colorado picks, you’ll want to see the college basketball predictions from the proven model at SportsLine.

The model simulates every Division 1 college basketball game 10,000 times. It enters Week 4 of the 2024-25 season on a 162-118 betting roll (+1762) on all top-rated college basketball picks dating back to 2023. Anyone following at sportsbooks and on betting apps has seen huge returns.

The model has set its sights on UConn vs. Colorado. You can head to SportsLine to see its picks. Here are several college basketball betting lines for the Colorado vs. UConn game:

• Colorado vs. UConn spread: UConn -15.5
• Colorado vs. UConn over/under: 143.5 points
• Colorado vs. UConn money line: UConn -1493, Colorado +853
• COL: The Buffaloes are 2-1 ATS over their last three games
• UCONN: The Huskies are 3-2 ATS this season
• Colorado vs. UConn picks: See picks here

Why Colorado can cover

Colorado had been performing well offensive, scoring at least 82 points in three straight games before a 72-56 loss to Michigan State on Monday. The Buffaloes won three of their first four games by at least 20 points coming off a 26-11 season, their most victories in program history as more than just the football program has seen a resurgence over recent years. Colorado has won more than 20 games in five of its last six seasons as Tad Boyle enters his 15th season as head coach with 13 winning seasons over his first 14 years. 

Elijah Malone, a two-time NAIA All-American before transferring to Colorado, leads the Buffaloes at 14 points per game. The 6-foot-10 senior also leads the team in blocks (1.6 per game) and is second in rebounding (5.6 per game) as a physical, imposing force in the paint. Andrej Jakimovski, a fifth-year senior transfer from Washington State, is second in scoring at 12.2 ppg. See which team to pick here.

Why UConn can cover

The Huskies certainly didn’t travel to Hawaii with intentions to play in the fifth-place side of the bracket, but after allowing Memphis to shoot 54.7% from the floor in Monday’s loss, that’s the situation UConn is in. The lack of defensive dominance is uncharacteristic for UConn, which is holding teams to 36.7% shooting this season, which ranks 17th in college basketball. The Huskies also have the 19th-best scoring defense in the country, allowing 60.6 ppg, so there’s reason to believe they’ll have a better defensive performance on Tuesday. 

A coach like Dan Hurley doesn’t typically take losing well, so you can expect it wasn’t a pleasant postgame locker room. UConn, the No. 2 team in the nation, still has two games left in Hawaii regardless of the results and it would be extremely detrimental to its ranking if the Huskies lose again this week, so you can expect a more focused effort on Tuesday. UConn has four players averaging at least 12.8 points per game, led by Alex Karaban’s 16.8 ppg, as the Huskies’ depth may be too much for Colorado. See which team to pick here.

How to make Colorado vs. UConn picks

The model has simulated UConn vs. Colorado 10,000 times and the results are in. The model is leaning Over, and it says one side of the spread hits more than 50% of the time. You can only see the pick at SportsLine.

So who wins UConn vs. Colorado, and which side of the spread hits more than 50% of the time? Visit SportsLine now to see which side of the Colorado vs. UConn spread you need to jump on, all from the model that is on a 162-118 roll on top-rated college basketball picks, and find out.