The Green Bay Packers (10-4) and New Orleans Saints (5-9) will square off in a NFC showdown on Monday Night Football to wrap up the Week 16 NFL schedule. The Saints have lost two of their last three matchups. Last week, the Commanders narrowly beat the Saints, 20-19. On the other sideline, Green Bay has won four of its last five games. Last week, the Packers torched the Seattle Seahawks, 30-13. Star running back Alvin Kamara (groin) and quarterback Derek Carr (hand) are out this week for the Saints.

Kickoff from Lambeau Field in Green Bay is set for 8:15 p.m. ET. Green Bay is a 14-point favorite in the latest Saints vs. Packers odds from the SportsLine Consensus, while the over/under for total points scored is 42.5. Before locking in any Packers vs. Saints picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2024 NFL season on an incredible 27-11 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 207-139 roll on top-rated NFL picks that dates back to the 2017 season and a 61-32 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns.

Now, the model has simulated Saints vs. Packers 10,000 times and just revealed its coveted NFL picks and NFL betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and NFL betting lines for Saints vs. Packers:

• Saints vs. Packers spread: Green Bay -14
• Saints vs. Packers over/under: 42.5 points
• Saints vs. Packers money line: Green Bay -1064, New Orleans +677
• NO: Saints are 6-8 against the spread this season 
• GB: Packers are 8-6 against the spread this season
• Saints vs. Packers picks: See picks at SportsLine
• Saints vs. Packers streaming: FuboTV (Try for free)

Why the Packers can cover

Quarterback Jordan Love heads into MNF tied for seventh in the league in touchdowns (23) with 2,953 passing yards. The Utah State product hasn’t thrown an interception and has a 100-plus passer rating in four straight games. In the win over the Seahawks, Love went 20-of-27 with 229 yards and two passing touchdowns.

Running back Josh Jacobs is a dominant runner in the backfield. The Alabama product is third in the NFL in carries (265) and rushing yards (1,147) and fourth in rushing touchdowns (12). He’s scored a touchdown in four straight games. See who to back at SportsLine.

Why the Saints can cover

Cornerback Alontae Taylor has been a consistent defender for the Saints. This season, Taylor has 79 total tackles, 13 pass deflections, four sacks and two forced fumbles. Linebacker Demario Davis has a nose for being around the ball, leading the team in total tackles (104) with six pass deflections. He’s recorded double-digit tackles in four games this season. 

Spencer Rattler is in line to start at quarterback. He rallied New Orleans from behind last week against Washington, hitting Foster Moreau for a touchdown with no time left, though the Saints were not able to convert the 2-point try. Still, New Orleans covered as a 7.5-point underdog, giving the Saints their third cover in their past five games. See who to back at SportsLine.

How to make Saints vs. Packers picks

The model is leaning Over the total, projecting 44 combined points. It also says one side of the spread has all the value. You can head to SportsLine to see the model’s picks. 

So who wins Packers vs. Saints on Monday Night Football, and which side of the spread has all the value? Visit SportsLine now to see which side of the Packers vs. Saints spread to back, all from the model that has returned well over $7,000 on top-rated NFL picks.