Preston North End welcome Oxford United to Deepdale on Saturday for just the second time in 25 years (15:00 GMT).
Both sides dwell in the bottom half of the table but did win to end 2024 on a positive note, each taking two wins in their final two fixtures.
However, while Oxford triumphed over Millwall at the start of 2025, Preston suffered a 3-1 loss to West Bromwich Albion.
A win for either side would see them pull further clear of danger but Preston will have to do something they have never done against a Gary Rowett side – win.
Preston North End will host Oxford United in any competition for the first time since March 2000 in the third tier, when they won 3-1 thanks to a brace from Brett Angell and a goal from Jon Macken.
Oxford United have won five of their last seven league meetings with Preston North End (L2), winning the reverse fixture 3-1 earlier this season.
Preston North End are unbeaten in each of their last six home league games (W2 D4), last going seven without loss at Deepdale in April 2023 (W4 D3).
Oxford United are winless in their last 10 matches played on a Saturday (D4 L6), since beating Stoke in September last year.
Oxford United manager Gary Rowett is unbeaten in 14 previous league meetings with Preston North End (W8 D6), the only opponent he has faced more than seven times without ever losing.
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