Devin Singletary, New York Giants

Status: Questionable vs. Seahawks

The Giants’ top back did not practice Thursday because of a groin injury. Singletary told ESPN he “has a chance” to suit up against Seattle.

Kenneth Walker III, Seattle Seahawks

Status: Questionable vs. Giants

Walker, who has an oblique injury, was limited in practice Thursday. After he missed a couple of games in a row, he returned to full power in Week 4 and had 80 yards rushing and three scores, so his absence would be massive.

Austin Ekeler, Washington Commanders

Status: Questionable vs. Browns

Ekeler looked to be on the way to a big performance against Cincinnati in Week 3 — 35 yards rushing and a score — but he sustained a concussion in the first half and was ruled out. He was a full participant at Thursday’s practice.

Brian Robinson, Washington Commanders

Status: Questionable vs. Browns

Robinson has been very productive this season (307 yards rushing, three touchdowns) but missed two straight practices with a knee injury. He did practice Thursday. He is day-to-day ahead of the home matchup vs. Cleveland.

Dameon Pierce, Houston Texans

Status: Questionable vs. Bills

Pierce missed practice Thursday dealing with a hamstring injury. He has not played since Week 1, in a win against the Colts in which he rushed three times for 16 yards.

Joe Mixon, Houston Texans

Status: Questionable vs. Bills

Another Houston running back could also be out vs. Buffalo this weekend. After a promising start, Mixon has not played since he injured an ankle in Week 2. NFL Network reports it is unlikely he plays Sunday.

If he and Pierce do not suit up, Cam Akers is expected to start in the backfield.

Jonathan Taylor, Indianapolis Colts

Status: Out vs. Jaguars

The Colts’ star running back has now missed two straight practices ahead of their matchup with the Jags with an ankle injury. He was officially ruled out Friday.

Travis Etienne, Jacksonville Jaguars

Status: Questionable vs. Colts

Etienne has been limited at practice this week with a shoulder injury he sustained in Week 4. He is considered day-to-day.

Wide receivers

Christian Watson, Green Bay Packers

Status: Doubtful vs. Rams

Watson did not practice Thursday while he was dealing with an ankle injury and is not expected to face Los Angeles.

Tank Dell, Houston Texans

Status: Questionable vs. Bills

Dell is battling a chest injury but has been a limited participant all week. He is trending toward playing against Buffalo.

Davante Adams, Las Vegas Raiders

Status: Questionable vs. Broncos

Adams, Las Vegas’ star pass catcher, has been the talk of the league after he requested a trade this week. He has a hamstring injury and is not expected to play Denver, according to ESPN.

Malik Nabers, New York Giants

Status: Out vs. Seahawks

Nabers left the Giants’ Week 4 game early with a concussion and has not practiced this week. He was ruled out Friday for this weekend.

Tight ends

Trey McBride, Arizona Cardinals

Status: Questionable vs. 49ers

McBride is looking to return from a concussion, and signs are good: He practiced in full Thursday and head coach Jonathan Gannon said he expects McBride to play.

David Njoku, Cleveland Browns

Status: Questionable vs. Commanders

Njoku has not played since he sprained an ankle in Week 1. He has practiced this week and after a planned day off Thursday, did practice on Friday.

Evan Ingram, Jacksonville Jaguars

Status: Questionable vs. Colts

Ingram has not played since Week 1 but has been a limited participant this week for Jacksonville and could suit up against Indianapolis.

Taysom Hill, New Orleans Saints

Status: Questionable vs. Chiefs

Hill, New Orleans’ do-everything “tight end,” has fractures to his ribs, according to head coach Dennis Allen. It does not appear likely he will play Monday against the Chiefs.