The Los Angeles Lakers hit the road looking to win their ninth straight game when they take on the Boston Celtics at the TD Garden on Saturday. Boston is 45-18 overall and 21-11 at home, while Los Angeles is 40-21 overall and 15-14 on the road. The Lakers are coming off a hard fought 113-109 overtime win over the New York Knicks on Thursday. The Celtics are looking to win their fourth straight after blowing out the Philadelphia 76ers 123-105. 

Tipoff in Boston is scheduled for 8:30 p.m. ET. The Celtics are favored by 7 points in the latest Lakers vs. Celtics odds via SportsLine consensus, and the over/under is 226.5 points. Before locking in any Celtics vs. Lakers picks, you’ll want to see the NBA predictions and betting advice from the proven computer simulation model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 20 of the 2024-25 NBA season on a sizzling 147-107 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It’s also an outstanding 18-10 (64%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has set its sights on Lakers vs. Celtics and just locked in its picks and NBA predictions. You can head to SportsLine now to see the model’s picks. Here are several NBA betting lines for the game:

• Lakers vs. Celtics spread: Celtics -7
• Lakers vs. Celtics over/under: 226.5 points
• Lakers vs. Celtics money line: Celtics -270, Lakers +219
• Lakers vs. Celtics picks: See picks at SportsLine
• Lakers vs. Celtics streaming: FuboTV (Try for free)

Why the Celtics can cover

The Celtics were dominant in their blowout win over the 76ers on Thursday. Boston won that game 123-105, and extended it against the spread winning streak to three games. Jayson Tatum scored 35 points and had seven rebounds in the win.

Tatum continues to lead the way and be a dominant force for Boston. The former Duke standout enters Saturday averaging 26.8 points, 8.8 rebounds, and 5.8 assists per game. His supporting cast includes Jaylen Brown (23.1 points, 6.1 rebounds, 4.8 assists per game) and Derrick White (16.7 points, 4.3 rebounds, and 4.3 assists per game). See which team to pick here.

Why the Lakers can cover

The Lakers are one of the hottest teams in the NBA right now. Los Angeles has won eight straight games, and is 18-3 in its last 21 games. The Lakers have climbed to second place in the Western Conference, and are 35-26 against the spread this season.

The duo of LeBron James and Luka Doncic lead the way for the Lakers. James, who turned 40-years-old this season, is averaging 25.1 points, 8.5 assists and 8.1 rebounds per game — all team highs. In 10 games with the Lakers, Doncic is averaging 23.8 points, 8.1 rebounds and 8.1 assists per game. See which team to pick here.

How to make Celtics vs. Lakers picks

The model has simulated Lakers vs. Celtics 10,000 times and the results are in. The model is leaning Over on the point total, and it’s also generated a point-spread pick that is hitting in almost 70% of simulations. You can only see the model’s pick at SportsLine.

So who wins Celtics vs. Lakers on Saturday, and which side of the spread hits in almost 70% of simulations? Visit SportsLine now to see which side of the Lakers vs. Celtics spread to back, all from the model that has returned well over $10,000 on top-rated NBA picks, and find out. 

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