Saturday was a rough day for some of college football’s most storied programs and highest-ranked teams as five of the top 11 teams in the AP Top 25 lost — with all five dropping games on the road.

Top-ranked Alabama lost 40-35 at Vanderbilt. No. 4 Tennessee lost 19-14 at Arkansas. No. 9 Missouri was blown out 41-10 at No. 25 Texas A&M.

And the upsets weren’t limited to the Southeastern Conference. In the Big Ten, No. 10 Michigan fell 27-17 at Washington. And No. 11 USC lost 24-17 at Minnesota.

And that might not be all the upsets, as No. 8 Miami was losing 14-10 early in the second quarter in the Hurricanes’ game at California.

With all the upsets, there is sure to be some significant shakeup at the top of the rankings when the new rankings are revealed on Sunday.

Of course, plenty of top teams still won this weekend, with No. 6 Oregon handling Michigan State 31-10, No. 3 Ohio State routing Iowa 35-7, No. 5 Georgia downing Auburn 31-13 and No. 7 Penn State beating UCLA 27-11. All four of those winners were playing at home.

The only AP Top 25 teams to win on the road were: No. 12 Ole Miss, which beat South Carolina 27-3; No. 15 Clemson, which beat Florida State 29-13; and No. 23 Indiana, which beat Northwestern 41-24.

— Joel Odom