The Kansas City Chiefs are the two-time defending Super Bowl champions and have won their first four games this season, but they are dealing with several key injuries heading into their Monday Night Football (8:15 p.m. ET) matchup against the New Orleans Saints. Running back Isiah Pacheco (leg) and wide receiver Rashee Rice (knee) are among the key playmakers sidelined, putting more pressure on quarterback Patrick Mahomes. He completed 19 of 29 passes for 245 yards and a touchdown in a road win against the Chargers last week, as tight end Travis Kelce had a team-high seven receptions for 89 yards. Kelce’s receiving yards over/under is 56.5 in the Week 5 NFL odds, while teammate Xavier Worthy’s total is 41.5 in the Chiefs vs. Saints props.

New Orleans ranks sixth in the NFL in points allowed per game (17.5), while the Chiefs are seventh (18.0). Should you be backing players to go Under their totals with your Week 5 NFL prop bets? Before betting any NFL props for Monday Night Football or entering NFL predictions on sites like PrizePicks, you need to see the Chiefs vs. Saints NFL prop predictions powered by SportsLine’s AI PickBot.

Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each player prop. The AI predictions are determined by statistically learning from each player’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score. 

Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. Last season, the AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. This year, it has already nailed 128 picks rated 4 stars or better. Anybody who followed those picks was way up.

For Chiefs vs. Saints NFL betting on Monday Night Football, the AI PickBot has evaluated the NFL player prop odds and provided Saints vs. Chiefs prop picks for every available prop market. You can only see the AI player prop predictions for Kanas City vs. New Orleans here.

Top NFL player prop bets for Chiefs vs. Saints

After analyzing Chiefs vs. Saints props and examining the dozens of NFL player prop markets, the AI PickBot says Saints quarterback Derek Carr goes under 211.5 passing yards. Carr was inconsistent last season, going under 200 passing yards on six occasions while cracking the 300-yard mark six times as well. He was held to just 142 passing yards in a loss to the Eagles two weeks ago, and he is facing a strong defense on Monday night in a difficult environment.

Carr has thrown an interception in three straight games and has been sacked in every game this season. The Saints have a top-10 rushing attack led by star running back Alvin Kamara, who they will lean on throughout this contest. The AI PickBot expects Kamara to get nearly 20 carries on Monday, which is one reason why Carr is going Under 211.5 passing yards in the latest projections. See more NFL props here.

How to make NFL player prop bets for Kansas City vs. New Orleans

In addition, the AI PickBot says one star sails past his rushing total and has five other NFL props rated 4 stars or better. You need to see the AI PickBot’s analysis before making any Saints vs. Chiefs prop bets for Monday Night Football.

Which Chiefs vs. Saints prop bets should you target for Monday Night Football? Visit SportsLine now to see the top Saints vs. Chiefs props, all from the SportsLine AI PickBot that nailed 1,674 top-rated picks last season and has hit 128 picks this year.